2008 Funded Research Projects

In its first year of operation, the Ben and Catherine Ivy Foundation is proud to have awarded $10.4 million for brain tumor research. These research projects reflect the Ivy Foundation’s commitment to funding Patient-Focused Research, which keeps the patient and relevant clinical issues at the center of every research project.

Below, please find a list of the Ivy Foundation funded research project titles, principal investigators (PIs) and award amounts. A summary of each research project is also available by clicking on the project title.

GLIOMA CANCER STEM CELLS AND TUMOR-DERIVED MESENCHYMAL STEM CELLS: ROLE AND CROSSTALK IN HUMAN GLIOMAS

PIs: Ken Aldape, MD and Fred Lang, MD, MD Anderson Cancer Center
Award: $1,500,000 over 3 years


IVY GENOMICS-BASED MEDICINE (G.B.M.) PROJECT –
STAGE I

PI and Consortium Leader: Mike Berens, PhD, Translational Genomics Research Institute (TGen)
Award: $3,240,343 over 2 years

Consortium member PIs:

  • Antonio Chiocca, MD, PhD and Sean Lawler, PhD, Ohio State University
  • Howard Colman, MD, PhD, M.D. Anderson Cancer Center
  • G.Yancey Gillespie, PhD, University of Alabama at Birmingham
  • C. David James, PhD, University of California, San Francisco
  • Tom Mikkelsen, MD, Henry Ford Hospital
  • Jann Sarkaria, MD, Mayo Clinic, Rochester
  • Andrew Sloan, MD, Case Western Reserve University School of Medicine
  • Craig Webb, PhD, Van Andel Research Institute

Consortium Collaboration Software: 5AM Solutions


TARGETING GLIOBLASTOMA THROUGH TUMOR ENDOTHELIAL MARKER-1 (TEM-1)

PI: George Coukos, MD, PhD, University of Pennsylvania
Award: $622,501 over 2 years

p75ntr IS A RATIONAL DRUG TARGET FOR MALIGNANT GLIOMA

PI: Peter A. Forsyth, MD, FRCPC, University of Calgary
Award: $1,277,005 over 3 years


DEVELOPMENT AND IMPLEMENTATION OF NOVEL MOLECULAR DIAGNOSTIC TOOLS TO GUIDE COMBINATION THERAPY FOR MALIGNANT GLIOMA PATIENTS

PIs: Paul Mischel, MD and Tim Cloughesy, MD, University of California, Los Angeles
Award: $1,500,000 over 3 years

THE IVY GBM ATLAS PROJECT: ANATOMIC GENE EXPRESSION ATLAS OF HUMAN GLIOBLASTOMA

PIs: Ralph Puchalski, PhD, Allen Institute for Brain Science and Greg Foltz, MD, Swedish Neuroscience Institute
Award: $2,118,946 over 3 years